Current Projects:

  1. Role of Microbiome (Liver-Gut-Brain Axis) in environmental-linked NAFLD.
  2. Microbiome alterations, gut-brain axis and Gulf War Illness Pathology.
  3. Exploring oxidative stress-epigenome signaling (DNA methylation, Histone modifications, micro RNAs) in obesity associated inflammatory liver diseases following environmental toxin and Gulf War Chemical exposure.
  4. Role of cationic channel protein TRPV4 in metabolic reprogramming of environment-linked nonalcoholic steatohepatitis (Chronic liver inflammation).
  5. Exploring the role of pattern recognition receptors (TLRS and NALP3) and Damage Associated Molecular Patterns (DAMPs, HMGB1, NAD) in toxicity associated nonalcoholic steatohepatitis.
  6. Role of adipocytokine leptin in redox-signaling and immune modulation in obesity associated disease.
  7. Modulation of Nonalcoholic Fatty Liver disease (NAFLD) by alternative medicinal compounds and methods