A joint study featuring researchers from Department of Epidemiology and Biostatistics and Environmental Health Sciences, funded by Chatterjee lab reports the association of disinfection byproducts of drinking water and its effects on US adult human population.
Monthly Archives: June 2015
TLR4 trafficking in gut
In a latest discovery, Chatterjee lab team members image TLR4 trafficking into the lipid rafts of distal small intestinal epithelial cells following nonalcoholic fatty liver disease mediated by NADPH oxidase subunit P47 phox. Team of Suvarthi Das and Varun Chandrashekaran conducted the study using the lab’s immunofluoresence microscopy facility.
NOS1 study accepted in J Exp Med
A study linked to NOS1 signaling led by Dr. Marcelo Bonini at University of Illinois at Chicago where Dr. Chatterjee is a collaborator was accepted for publication in the Journal of Experimental Medicine, a premier journal in the field of Biomedical research. The study that links NOS1 to NFkB signaling via SOCS-1 is a breakthrough Continue Reading
Congratulations to Suvarthi for her article in Am J Path
Toll like receptors have to navigate their way into the lipid rafts for their signaling mechanisms. Suvarthi’s study showed for the first time that peroxynitrite drives TLR4 trafficking onto the lipid rafts, a feature previously unknown in nonalcoholic steatohepatitis.